resistance to drugs

Relapses of the malady, ineffectiveness of different drug regimens and even resistance to drugs are emerging.

疾病的反复发作, 不同药物治疗方案的无效,甚至耐药性正在出现.

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Multidrug resistance ( MDR) is characterized by cross-resistance to a variety of drugs with different structure and function.

多药耐药（Multidrug Resistance，MDR）是指细胞对一种化疗药物出现耐药的同时，对其他结构不同、作用靶位不同的化疗药物亦产生抗药性。

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Developing resistance to drugs and insecticides is part of the problem but funding levels have also reduced.

对药物和杀虫剂产生抗药性是问题之一，但与此同时，针对疟疾的研究资金也有所降低。

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But these mechanisms can not explain cross-resistance to other chemotherapy drugs.

但仅用这些机制不能解释在研究中发现的当对MTX出现耐药后也会对其它抗癌机理不同于MTX的其它化疗药物耐药.

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Many drugs can be used to cure ovarian cancer at present, but the drug resistance to chemotherapy of ovarian cancer patients has become the important influence factor to impact the 5-year survival rate.

目前可供临床使用的治疗卵巢癌的药物种类较多，但卵巢癌对化疗的耐药性已经成为影响患者五年生存率的重要因素。

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the research on mechanisms of resistance to drugs in trypanosomes

锥虫抗药性的原因与机制研究进展

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The occurrence of cross-resistance to structurally and functionally unrelated drugs, called multidrug resistsance ( MDR), is a main cause of failure in the chemotherapy of leukemia.

但是，多数白血病病人的治疗仍以失败而告终。对化疗药物产生多药耐药性（MDR）是白血病治疗失败的主要原因。

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Viruses that have evolved resistance to HIV drugs are tagged to appear green, while those that have not are tagged to appear red.

发展成抗HIV药的耐药株的病毒被标记并呈绿色，而那些没有被标记的显红色。

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establishment and identification of the gene cell line transfected aldose reductase like gene and its drug resistance to drugs containing carbonyl group

醛糖还原酶相似基因转染细胞对含碳酰基抗癌药物耐药的研究

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Development of studies on mechanisms of resistance to drugs in trypanosomes

锥虫抗药性机制的研究进展

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Reversional effect of verapamil and other 5 drugs on the resistance to cisplatin in human ovarian cancer cell line

维拉帕米等6种药物对人卵巢癌细胞系顺铂耐药性的逆转作用

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CONCLUSIONS Hospital acquired infection of deep fungus and resistance had an increasing tendency, evident resistance had been found in some antifungal drugs, especially azoles. So it is the time to take some effective control means.

结论深部真菌医院感染及耐药性呈上升趋势，特别是唑类抗真菌药已呈明显耐药，采用有效的防治措施刻不容缓。

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Multidrug resistance is frequently linked with DNA elements such as integrons, which can be located on transposons and plasmids but also on the chromosome. They can integrate and disseminate genes encoding resistance to a number of antimicrobial drugs.

多重耐药细菌往往携带诸如整合子等基因元件。整合子位于质粒、转座子和基因组上，它们可以整合并且传播大量的耐药基因。

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Ess positive strains have multiple resistance to drugs.

ESS阳性 株多重耐药性较多见.

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